article · 09/02/2015
Synthesis of Programmable Reaction-Diffusion Fronts Using DNA Catalyzers
Résumé
We introduce a DNA-based reaction-diffusion (RD) system in which reaction and diffusion terms can be precisely and independently controlled. The effective diffusion coefficient of an individual reaction component, as we demonstrate on a traveling wave, can be reduced up to 2.7-fold using a self-assembled hydrodynamic drag. The intrinsic programmability of this RD system allows us to engineer, for the first time, orthogonal autocatalysts that counterpropagate with minimal interaction. Our results are in excellent quantitative agreement with predictions of the Fisher-Kolmogorov-Petrovskii-Piscunov model. These advances open the way for the rational engineering of pattern formation in pure chemical RD systems.
Citer cet article
Zadorin, A.-S., Rondelez, Y., Galas, J.-C., & Estevez-Torres, A. (2015). Synthesis of Programmable Reaction-Diffusion Fronts Using DNA Catalyzers. Phys. Rev. Lett., 114(6). https://doi.org/10.1103/PhysRevLett.114.068301@article{Zadorin2015_89,
author = {Zadorin, Anton S. and Rondelez, Yannick and Galas, Jean-Christophe and Estevez-Torres, Andre},
year = {2015},
month = {2},
title = {Synthesis of Programmable Reaction-Diffusion Fronts Using DNA Catalyzers},
journal = {Phys. Rev. Lett.},
publisher = {AMER PHYSICAL SOC},
volume = {114},
number = {6},
address = {ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA},
abstract = {We introduce a DNA-based reaction-diffusion (RD) system in which reaction and diffusion terms can be precisely and independently controlled. The effective diffusion coefficient of an individual reaction component, as we demonstrate on a traveling wave, can be reduced up to 2.7-fold using a self-assembled hydrodynamic drag. The intrinsic programmability of this RD system allows us to engineer, for the first time, orthogonal autocatalysts that counterpropagate with minimal interaction. Our results are in excellent quantitative agreement with predictions of the Fisher-Kolmogorov-Petrovskii-Piscunov model. These advances open the way for the rational engineering of pattern formation in pure chemical RD systems.},
url = {http://www.dx.doi.org/10.1103/PhysRevLett.114.068301},
doi = {10.1103/PhysRevLett.114.068301},
issn = {0031-9007},
}TY - JOUR
AU - Zadorin, Anton S.
AU - Rondelez, Yannick
AU - Galas, Jean-Christophe
AU - Estevez-Torres, Andre
PY - 2015
DA - 2015/02/09
TI - Synthesis of Programmable Reaction-Diffusion Fronts Using DNA Catalyzers
JO - Phys. Rev. Lett.
VL - 114
IS - 6
PB - AMER PHYSICAL SOC
SN - 0031-9007
AB - We introduce a DNA-based reaction-diffusion (RD) system in which reaction and diffusion terms can be precisely and independently controlled. The effective diffusion coefficient of an individual reaction component, as we demonstrate on a traveling wave, can be reduced up to 2.7-fold using a self-assembled hydrodynamic drag. The intrinsic programmability of this RD system allows us to engineer, for the first time, orthogonal autocatalysts that counterpropagate with minimal interaction. Our results are in excellent quantitative agreement with predictions of the Fisher-Kolmogorov-Petrovskii-Piscunov model. These advances open the way for the rational engineering of pattern formation in pure chemical RD systems.
DO - 10.1103/PhysRevLett.114.068301
UR - http://www.dx.doi.org/10.1103/PhysRevLett.114.068301
ER -