Absorption Band III Kinetics Probe the Picosecond Heme Iron Motion Triggered by Nitric Oxide Binding to Hemoglobin and Myoglobin

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Yoo, B.-K., Kruglik, S.-G., Lamarre, I., Martin, J.-L., & Negrerie, M. (2012). Absorption Band III Kinetics Probe the Picosecond Heme Iron Motion Triggered by Nitric Oxide Binding to Hemoglobin and Myoglobin. Journal of Physical Chemistry B, 116(13), 4106-4114. https://doi.org/10.1021/jp300849y

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@article{Yoo2012_31,
  author = {Yoo, Byung-Kuk and Kruglik, Sergei G. and Lamarre, Isabelle and Martin, Jean-Louis and Negrerie, Michel},
  year = {2012},
  month = {4},
  title = {Absorption Band III Kinetics Probe the Picosecond Heme Iron Motion Triggered by Nitric Oxide Binding to Hemoglobin and Myoglobin},
  journal = {Journal of Physical Chemistry B},
  publisher = {AMER CHEMICAL SOC},
  volume = {116},
  number = {13},
  pages = {4106-4114},
  address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
  abstract = {To study the ultrafast movement of the heme iron induced by nitric oxide (NO) binding to hemoglobin (Hb) and myoglobin (Mb), we probed the picosecond spectral evolution of absorption band III (similar to 760 nm) and vibrational modes (iron-histidine stretching, v(4) and v(7) in-plane modes) in time-resolved resonance Raman spectra. The time constants of band III intensity kinetics induced by NO rebinding (25 ps for hemoglobin and 40 ps for myoglobin) are larger than in Soret bands and Q bands. Band III intensity kinetics is retarded with respect to NO rebinding to Hb and to Mb. Similarly, the v((Fe-His)) stretching intensity kinetics are retarded with respect to the v(4) and v(7) heme modes and to Soret absorption. In contrast, band III spectral shift kinetics do not coincide with band III intensity kinetics but follows Soret kinetics. We concluded that, namely, the band III intensity depends on the heme iron out-of-plane position, as theoretically predicted (Stavrov, S. S. Biopolymers 2004, 74, 37-40).},
  url = {http://www.dx.doi.org/10.1021/jp300849y},
  doi = {10.1021/jp300849y},
  issn = {1520-6106},
}

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TY  - JOUR
AU  - Yoo, Byung-Kuk
AU  - Kruglik, Sergei G.
AU  - Lamarre, Isabelle
AU  - Martin, Jean-Louis
AU  - Negrerie, Michel
PY  - 2012
DA  - 2012/04/05
TI  - Absorption Band III Kinetics Probe the Picosecond Heme Iron Motion Triggered by Nitric Oxide Binding to Hemoglobin and Myoglobin
JO  - Journal of Physical Chemistry B
VL  - 116
IS  - 13
PB  - AMER CHEMICAL SOC
SN  - 1520-6106
AB  - To study the ultrafast movement of the heme iron induced by nitric oxide (NO) binding to hemoglobin (Hb) and myoglobin (Mb), we probed the picosecond spectral evolution of absorption band III (similar to 760 nm) and vibrational modes (iron-histidine stretching, v(4) and v(7) in-plane modes) in time-resolved resonance Raman spectra. The time constants of band III intensity kinetics induced by NO rebinding (25 ps for hemoglobin and 40 ps for myoglobin) are larger than in Soret bands and Q bands. Band III intensity kinetics is retarded with respect to NO rebinding to Hb and to Mb. Similarly, the v((Fe-His)) stretching intensity kinetics are retarded with respect to the v(4) and v(7) heme modes and to Soret absorption. In contrast, band III spectral shift kinetics do not coincide with band III intensity kinetics but follows Soret kinetics. We concluded that, namely, the band III intensity depends on the heme iron out-of-plane position, as theoretically predicted (Stavrov, S. S. Biopolymers 2004, 74, 37-40).
SP  - 4106
EP  - 4114
DO  - 10.1021/jp300849y
UR  - http://www.dx.doi.org/10.1021/jp300849y
ER  -