Séminaires
376 événement(s)
Anne-Florence Bitbol
Inférer quelles protéines interagissent spécifiquement à partir de leurs séquences
Specific protein-protein interactions play crucial roles in the stability of multi-protein complexes and in signal transduction. Thus, mapping these interactions is key to a systems-level understanding of cells....
David Bikard
Interactions between DNA repair pathways and CRISPR-Cas systems in Bacteria
CRISPR-Cas systems confer bacteria and archaea an adaptive immunity against phages and other invading mobile genetic elements. In type II CRISPR-Cas systems, the Cas9 protein introduces double strand breaks in target...
Gilles Fischer (UPMC)
Quantitative principles of genome evolution revealed by ancestral genome reconstruction
Comparative genomics is a powerful approach to understand genome evolutionacross species. The study of synteny conservation between multiple speciesallowed critical conceptual advances on how genomes are...
Jérôme Wong Ng
Addressing the functionality of adaptation in Chemotaxis
A notable feature of bacterial chemotaxis is adaptation : after the application of a step stimulus, the bacterial running time relaxes to its pre-stimulus level. The response to the amino acid aspartate is precisely...
Brice Bathellier
Cortical bases of temporal asymmetries in auditory perception.
"Sound recognition relies not only on spectral but also on temporal cues as evidenced by the profound perceptual impact of time-reversion on common sounds. To address the coding principles underlying such temporal...
Arnaud Huguet (UPMC
Application des lipides microbiens à l'étude des milieux naturels
Les lipides membranaires d’origine microbienne peuvent permettre de mieux comprendre le fonctionnement hydrogéochimique des écosystèmes terrestres et aquatiques. Les microorganismes sont en effet capables d’ajuster...
Mark Isalan (Imperial College
Engineering synthetic developmental patterns: how many ways can you make a stripe?
Synthetic biology is a promising tool to study the function and properties of gene regulatory networks. Gene circuits with predefined behaviors have been successfully built and modeled, but largely on a case-by-case...
Vincent Noireaux (University of Minnesota)
Cell-free transcription-translation: from gene circuits to self-assembly in a test tube
Originally developed to decipher the genetic code and study gene regulation, cell-free transcription-translation (TX-TL) systems are becoming powerful platforms to construct biological systems in vitro through the...